In the story, Angela is Grace Wexler's daughter. Angela's relationship with Grace is dysfunctional and fraught with conflict. As a domineering and opinionated mother, Grace imposes her will on Angela without consideration or sympathy.
Eventually, Angela Wexler rebels against her mother's vision of a perfect daughter and goes back to college to become an orthopedic surgeon. At the beginning of the story, she is engaged to be married to Dr. Denton Deere, a plastic surgery intern at St. Joseph's Hospital, but she soon breaks off their engagement to finish her medical studies. Later in the novel, Turtle tells Julian Eastman that Angela is an orthopedic surgeon, so she does graduate from medical school.
After five years, Angela meets Denton again. He is now a neurologist but has never gotten married. As the story concludes, we find out that Angela and Denton do eventually marry, and they have a little girl by the name of Alice.
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